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Prostate Brachytherapy (or implant) is rapidly becoming an alternative treatment for early and advanced stages of prostate cancer.   AROS provides the Central Valley's only complete and active prostate implant program.   We have carried out over 150 implants over the past year (both seed & HDR) well above national implant standards.

Prostate Seed Implant

--->Click here for information on HDR implants

Equipment -- We have the Variseed/MMS seed implant planning system and the latest in ultrasound seed implant technology.  We have the capability to monitor and modify seed implant process in the operating room with the 3-dimensional planning system.

         

    B & K Ultrasound System                         Seed Needle Loading Chart

Experience -- Our radiation oncologist (Drs Ramsinghani), urologists, physicists, nurses and dosimetrists have all completed training at the Swedish Prostate Institute for the seed implant technique.

     

Patient Selection --  Some but not all patients are candidates for seed implants.  Patients with early stage cancer, low PSA levels (< 10) and low to moderately aggressive cancers are candidates.  Some patients will need hormonal injections and/or hormonal pills prior to the implant to reduce the size of the prostate gland. A small fraction of these patients may not be suitable for implantation due to the size of the prostate, the narrowness of their pubic bones or patient health.  Also patients with a high Gleason score (7 or higher) may require external radiation treatments and hormone treatments as well.

Gleason Score from Biopsy 

Implant Process - -  Patients will need a special ultrasound study 2 weeks before the implant to determine the number and distribution of the seeds in the prostate.  The implant will be carried out under a spinal anesthetic (like an epidural) and 75-150 seeds will be implanted into the prostate with 25-40 needles under ultrasound.  The procedure takes approximately 45 minutes and patients may be suitable for discharge the same day--making the procedure an outpatient procedure in many patients.

 

Above:   Patient placement in OR                           Above:    Needle Placement

Below:   Fluoroscopy and adding extra seeds    

Transrectal Ultrasound Guidance:   With the aid of the transrectal ultrasound, needles are advanced into the prostate and the seeds deposited at the appropriate depth and location.  Our B&K Leopard Ultrasound system is the latest technology and delivers precise transverse and saggital images through the prostate.

Below:   Transverse ultrasound view             Below:  Saggital ultrasound view of prostate

Results -- 10yr results now show equivalent long term success with seeds as compared to surgery or external radiotherapy.  Our implants are assessed post-operatively with a CT scan to confirm the distribution of the seeds.  An 80% score is considered a successful implant by most centers; we are consistently obtaining results in the 85-99% range.

Right:  Post-implant CT scan & Planning to verify accuracy of implant  -->

 

Prostate HDR Implants

High Dose Rate (HDR) -- HDR implants are delivered via a small radioactive iridium 192 source that can be programmed to deliver a specific amount of radiation for a set time to the prostate.   Small plastic catheters are implanted into the prostate under ultrasound guidance similar to the seed implant technique above for 48 hours.  No radioactive sources are permanently left in the patient.  A five-week course of radiation will follow the HDR implant to the prostate.

    Above:  HDR treatment tube                        Above:  HDR dummy seeds

   Below:    HDR catheters                               Below:  Placement of catheters

 

Left:  HDR catheters attached to treatment tubes

         and HDR unit

 

 

 

Results -- Although HDR implants can be given to most prostate patients, the greatest benefit will be those with more advanced cancers that are localized to the prostate.   Published studies now indicate that at 5 years, prostate HDR with 5 weeks of external radiation yield PSA-free failures of 84% as compared to 47% for surgery or 8 weeks of radiation of only 47%.

For More Information Contact:


Dr. Veena Ramsinghani 

 


Advanced Radiation Oncology Services
7130 N. Millbrook Ave #112

Fresno, California 93720
Tel:   559-624-5210


 

Last modified: January 17, 2002.